Therefore, the 5-year survival rate of OTSCC patients is still unsatisfactory even with combined treatments involving surgery, radiotherapy and chemotherapy 6, 7. It has been reported that about 40–60% patients suffer from local recurrence or lymph node metastasis within 5 years 5. High rates of local recurrence and cervical lymph node metastasis are the most notorious clinical behaviors of OTSCC 3, 4. Oral tongue squamous cell carcinoma (OTSCC) is one of the most frequently diagnosed tumor and the leading causes of death among head and neck cancers 1, 2. The nomogram based on nutritional and immune-related indicators represents a promising tool for outcome prediction of surgical OTSCC. Based on the cutoff value obtained from the nomogram, the proposed high-risk group had poorer OS than low-risk group ( p < 0.0001). The nomogram also had a good calibration and improved overall net benefit. The bootstrap-corrected concordance index of nomogram was higher than that of pTNM stage (0.794 vs. The Akaike Information Criterion and Bayesian Information Criterion of the nomogram were lower than those of pTNM stage, indicating a better goodness-of-fit of the nomogram for predicting OS. pTNM stage, age and total protein, immunoglobulin G, factor B and red blood cell count were identified as independent prognostic factors to create the nomogram. A nomogram based on Cox regression analysis results was established and internally validated using bootstrap resampling method. 169 TSCC patients who underwent surgical treatments in the Cancer Hospital of Shantou University Medical College were included. The aim of this study was to establish a nomogram to predict overall survival (OS) of TSCC patients after surgery. Oral tongue squamous cell carcinoma (OTSCC) is one of the most aggressive oral tumors.

Immune system indicators